Characterizing and optimizing poly- L-lactide-co-1-caprolactone membranes for urothelial tissue engineering
نویسندگان
چکیده
Institute of Biomedical Technology, University of Tampere, Tampere, Finland BioMediTech, Tampere, Finland Science Centre, and Department of Eye, Ear and Oral Diseases, Tampere University Hospital, Tampere, Finland Department of Biomedical Engineering, Tampere University of Technology, Tampere, Finland Paediatric and Adolescent Surgery Unit, Paediatric Research Centre and Tampere University Hospital, Tampere, Finland Department of Biomaterials Science and Technology, University of Twente, Enschede, The Netherlands
منابع مشابه
Characterizing and optimizing poly-L-lactide-co-ε-caprolactone membranes for urothelial tissue engineering.
Different synthetic biomaterials such as polylactide (PLA), polycaprolactone and poly-l-lactide-co-ε-caprolactone (PLCL) have been studied for urothelial tissue engineering, with favourable results. The aim of this research was to further optimize the growth surface for human urothelial cells (hUCs) by comparing different PLCL-based membranes: smooth (s) and textured (t) PLCL and knitted PLA me...
متن کاملComparison of a poly-L-lactide-co-ε-caprolactone and human amniotic membrane for urothelium tissue engineering applications.
The reconstructive surgery of urothelial defects, such as severe hypospadias is susceptible to complications. The major problem is the lack of suitable grafting materials. Therefore, finding alternative treatments such as reconstruction of urethra using tissue engineering is essential. The aim of this study was to compare the effects of naturally derived acellular human amniotic membrane (hAM) ...
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Electrospinning can produce nanofibrous scaffolds that mimic the architecture of the extracellular matrix and support cell attachment for tissue engineering applications. In this study, fibrous membranes of polyhydroxybutyrate (PHB) with various loadings of poly(L-lactide-co-ε-caprolactone) (PLCL) were successfully prepared by electrospinning. In comparison to PLCL scaffolds, PLCL blends with P...
متن کاملComparison of a poly-L-lactide-co-1- caprolactone and human amniotic membrane for urothelium tissue engineering applications
Regea–Institute for Regenerative Medicine, University of Tampere, Tampere, Finland Science Centre, University of Tampere, Tampere, Finland Department of Biomedical Engineering, Tampere University of Technology, Tampere, Finland Department of Eye, Ear and Oral Diseases, Tampere University Hospital, Tampere, Finland Paediatric and Adolescent Surgery Unit, Pediatric Research Centre and Tampere Uni...
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Because of the wide use of biodegradable materials in tissue engineering, it is necessary to obtain biocompatible polymers with different mechanical and physical properties as well as degradation ratio. Novel co- and terpolymers of various composition and chain microstructure have been developed and applied for cell culture. The aim of this study was to evaluate the adhesion and proliferation o...
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